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DiMo Brand names, DiMo Analogs

DiMo Brand Names Mixture

  • No information avaliable

DiMo Chemical_Formula

C17H19NO3

DiMo RX_link

http://www.rxlist.com/cgi/generic/hydromorphone.htm

DiMo fda sheet

DiMo FDA

DiMo msds (material safety sheet)

DiMo MSDS

DiMo Synthesis Reference

No information avaliable

DiMo Molecular Weight

285.338 g/mol

DiMo Melting Point

266-267 oC

DiMo H2O Solubility

No information avaliable

DiMo State

Solid

DiMo LogP

1.28 (Roy, SD; Flynn, GL Pharm. Res. 5:580 (1988))

DiMo Dosage Forms

Capsule (controlled-delivery); Solution; Tablet

DiMo Indication

For the relief of moderate to severe pain such as that due to surgery, cancer, trauma/injury, burns, myocardial infarction and colic.

DiMo Pharmacology

Hydromorphone is a hydrogenated ketone derivative of morphine that acts as a narcotic analgesic. It has a shorter duration of action than morphine. Hydromorphone is approximately 8 times more potent on a milligram basis than morphine. In addition, hydromorphone is better absorbed orally than is morphine. In clinical settings, Hydromorphone exerts its principal pharmacological effect on the central nervous system and gastrointestinal tract. Its primary actions of therapeutic value are analgesia and sedation. Hydromorphone appears to increase the patient's tolerance for pain and to decrease discomfort, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Opioids also produce respiratory depression by direct action on brain stem respiratory centers.

DiMo Absorption

Better absorbed orally than morphine

DiMo side effects and Toxicity

Hydromorphone is a schedule II narcotic which can lead to physical dependence or addiction. High doses lead to respiratory depression, nausea, and vomiting. Overdoses lead to extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur.

DiMo Patient Information

http://www.drugs.com/cons/Hydroflumethiazide.html

DiMo Organisms Affected

Humans and other mammals