Dihydromorfinon en es it fr

Dihydromorfinon Brand names, Dihydromorfinon Analogs

Dihydromorfinon Brand Names Mixture

  • No information avaliable

Dihydromorfinon Chemical_Formula

C17H19NO3

Dihydromorfinon RX_link

http://www.rxlist.com/cgi/generic/hydromorphone.htm

Dihydromorfinon fda sheet

Dihydromorfinon FDA

Dihydromorfinon msds (material safety sheet)

Dihydromorfinon MSDS

Dihydromorfinon Synthesis Reference

No information avaliable

Dihydromorfinon Molecular Weight

285.338 g/mol

Dihydromorfinon Melting Point

266-267 oC

Dihydromorfinon H2O Solubility

No information avaliable

Dihydromorfinon State

Solid

Dihydromorfinon LogP

1.28 (Roy, SD; Flynn, GL Pharm. Res. 5:580 (1988))

Dihydromorfinon Dosage Forms

Capsule (controlled-delivery); Solution; Tablet

Dihydromorfinon Indication

For the relief of moderate to severe pain such as that due to surgery, cancer, trauma/injury, burns, myocardial infarction and colic.

Dihydromorfinon Pharmacology

Hydromorphone is a hydrogenated ketone derivative of morphine that acts as a narcotic analgesic. It has a shorter duration of action than morphine. Hydromorphone is approximately 8 times more potent on a milligram basis than morphine. In addition, hydromorphone is better absorbed orally than is morphine. In clinical settings, Hydromorphone exerts its principal pharmacological effect on the central nervous system and gastrointestinal tract. Its primary actions of therapeutic value are analgesia and sedation. Hydromorphone appears to increase the patient's tolerance for pain and to decrease discomfort, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Opioids also produce respiratory depression by direct action on brain stem respiratory centers.

Dihydromorfinon Absorption

Better absorbed orally than morphine

Dihydromorfinon side effects and Toxicity

Hydromorphone is a schedule II narcotic which can lead to physical dependence or addiction. High doses lead to respiratory depression, nausea, and vomiting. Overdoses lead to extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur.

Dihydromorfinon Patient Information

http://www.drugs.com/cons/Hydroflumethiazide.html

Dihydromorfinon Organisms Affected

Humans and other mammals