Hexadecylpyridinium chloride monohydrate
Brand names,
Hexadecylpyridinium chloride monohydrate
Analogs
Hexadecylpyridinium chloride monohydrate
Brand Names Mixture
Hexadecylpyridinium chloride monohydrate
Chemical_Formula
No information avaliable
Hexadecylpyridinium chloride monohydrate
RX_link
http://www.rxlist.com/cgi/generic2/cetrorelix.htm
Hexadecylpyridinium chloride monohydrate
fda sheet
Hexadecylpyridinium chloride monohydrate
msds (material safety sheet)
Hexadecylpyridinium chloride monohydrate
Synthesis Reference
No information avaliable
Hexadecylpyridinium chloride monohydrate
Molecular Weight
1431.06 g/mol
Hexadecylpyridinium chloride monohydrate
Melting Point
No information avaliable
Hexadecylpyridinium chloride monohydrate
H2O Solubility
No information avaliable
Hexadecylpyridinium chloride monohydrate
State
Solid
Hexadecylpyridinium chloride monohydrate
LogP
No information avaliable
Hexadecylpyridinium chloride monohydrate
Dosage Forms
Powder for solution
Hexadecylpyridinium chloride monohydrate
Indication
For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.
Hexadecylpyridinium chloride monohydrate
Pharmacology
Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.
Hexadecylpyridinium chloride monohydrate
Absorption
Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.
Hexadecylpyridinium chloride monohydrate
side effects and Toxicity
No information avaliable
Hexadecylpyridinium chloride monohydrate
Patient Information
Hexadecylpyridinium chloride monohydrate
Organisms Affected
Humans and other mammals