Hexadecyl pyridinium bromide
Brand names,
Hexadecyl pyridinium bromide
Analogs
Hexadecyl pyridinium bromide
Brand Names Mixture
Hexadecyl pyridinium bromide
Chemical_Formula
No information avaliable
Hexadecyl pyridinium bromide
RX_link
http://www.rxlist.com/cgi/generic2/cetrorelix.htm
Hexadecyl pyridinium bromide
fda sheet
Hexadecyl pyridinium bromide
msds (material safety sheet)
Hexadecyl pyridinium bromide
Synthesis Reference
No information avaliable
Hexadecyl pyridinium bromide
Molecular Weight
1431.06 g/mol
Hexadecyl pyridinium bromide
Melting Point
No information avaliable
Hexadecyl pyridinium bromide
H2O Solubility
No information avaliable
Hexadecyl pyridinium bromide
State
Solid
Hexadecyl pyridinium bromide
LogP
No information avaliable
Hexadecyl pyridinium bromide
Dosage Forms
Powder for solution
Hexadecyl pyridinium bromide
Indication
For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.
Hexadecyl pyridinium bromide
Pharmacology
Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.
Hexadecyl pyridinium bromide
Absorption
Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.
Hexadecyl pyridinium bromide
side effects and Toxicity
No information avaliable
Hexadecyl pyridinium bromide
Patient Information
Hexadecyl pyridinium bromide
Organisms Affected
Humans and other mammals