Cetyl pyridinium chloride
Brand names,
Cetyl pyridinium chloride
Analogs
Cetyl pyridinium chloride
Brand Names Mixture
Cetyl pyridinium chloride
Chemical_Formula
No information avaliable
Cetyl pyridinium chloride
RX_link
http://www.rxlist.com/cgi/generic2/cetrorelix.htm
Cetyl pyridinium chloride
fda sheet
Cetyl pyridinium chloride
msds (material safety sheet)
Cetyl pyridinium chloride
Synthesis Reference
No information avaliable
Cetyl pyridinium chloride
Molecular Weight
1431.06 g/mol
Cetyl pyridinium chloride
Melting Point
No information avaliable
Cetyl pyridinium chloride
H2O Solubility
No information avaliable
Cetyl pyridinium chloride
State
Solid
Cetyl pyridinium chloride
LogP
No information avaliable
Cetyl pyridinium chloride
Dosage Forms
Powder for solution
Cetyl pyridinium chloride
Indication
For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.
Cetyl pyridinium chloride
Pharmacology
Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.
Cetyl pyridinium chloride
Absorption
Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.
Cetyl pyridinium chloride
side effects and Toxicity
No information avaliable
Cetyl pyridinium chloride
Patient Information
Cetyl pyridinium chloride
Organisms Affected
Humans and other mammals