Chondroitin hydrochloride
Brand names,
Chondroitin hydrochloride
Analogs
Chondroitin hydrochloride
Brand Names Mixture
Chondroitin hydrochloride
Chemical_Formula
No information avaliable
Chondroitin hydrochloride
RX_link
http://www.rxlist.com/cgi/generic2/cetrorelix.htm
Chondroitin hydrochloride
fda sheet
Chondroitin hydrochloride
msds (material safety sheet)
Chondroitin hydrochloride
Synthesis Reference
No information avaliable
Chondroitin hydrochloride
Molecular Weight
1431.06 g/mol
Chondroitin hydrochloride
Melting Point
No information avaliable
Chondroitin hydrochloride
H2O Solubility
No information avaliable
Chondroitin hydrochloride
State
Solid
Chondroitin hydrochloride
LogP
No information avaliable
Chondroitin hydrochloride
Dosage Forms
Powder for solution
Chondroitin hydrochloride
Indication
For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.
Chondroitin hydrochloride
Pharmacology
Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.
Chondroitin hydrochloride
Absorption
Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.
Chondroitin hydrochloride
side effects and Toxicity
No information avaliable
Chondroitin hydrochloride
Patient Information
Chondroitin hydrochloride
Organisms Affected
Humans and other mammals