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Cetrorelixum [Inn-Latin] en es it fr

Cetrorelixum [Inn-Latin] Brand names, Cetrorelixum [Inn-Latin] Analogs

Cetrorelixum [Inn-Latin] Brand Names Mixture

  • No information avaliable

Cetrorelixum [Inn-Latin] Chemical_Formula

No information avaliable

Cetrorelixum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic2/cetrorelix.htm

Cetrorelixum [Inn-Latin] fda sheet

Cetrorelixum_[Inn-Latin] FDA

Cetrorelixum [Inn-Latin] msds (material safety sheet)

Cetrorelixum [Inn-Latin] Synthesis Reference

No information avaliable

Cetrorelixum [Inn-Latin] Molecular Weight

1431.06 g/mol

Cetrorelixum [Inn-Latin] Melting Point

No information avaliable

Cetrorelixum [Inn-Latin] H2O Solubility

No information avaliable

Cetrorelixum [Inn-Latin] State

Solid

Cetrorelixum [Inn-Latin] LogP

No information avaliable

Cetrorelixum [Inn-Latin] Dosage Forms

Powder for solution

Cetrorelixum [Inn-Latin] Indication

For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.

Cetrorelixum [Inn-Latin] Pharmacology

Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.

Cetrorelixum [Inn-Latin] Absorption

Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.

Cetrorelixum [Inn-Latin] side effects and Toxicity

No information avaliable

Cetrorelixum [Inn-Latin] Patient Information

Cetrorelixum [Inn-Latin] Organisms Affected

Humans and other mammals