Cetrorelix acetate en es it fr

Cetrorelix acetate Brand names, Cetrorelix acetate Analogs

Cetrorelix acetate Brand Names Mixture

  • No information avaliable

Cetrorelix acetate Chemical_Formula

No information avaliable

Cetrorelix acetate RX_link

http://www.rxlist.com/cgi/generic2/cetrorelix.htm

Cetrorelix acetate fda sheet

Cetrorelix_acetate FDA

Cetrorelix acetate msds (material safety sheet)

Cetrorelix acetate Synthesis Reference

No information avaliable

Cetrorelix acetate Molecular Weight

1431.06 g/mol

Cetrorelix acetate Melting Point

No information avaliable

Cetrorelix acetate H2O Solubility

No information avaliable

Cetrorelix acetate State

Solid

Cetrorelix acetate LogP

No information avaliable

Cetrorelix acetate Dosage Forms

Powder for solution

Cetrorelix acetate Indication

For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.

Cetrorelix acetate Pharmacology

Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.

Cetrorelix acetate Absorption

Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.

Cetrorelix acetate side effects and Toxicity

No information avaliable

Cetrorelix acetate Patient Information

Cetrorelix acetate Organisms Affected

Humans and other mammals