Cetrotide
Cetrotide Brand names, Cetrotide Analogs
Cetrotide Brand Names Mixture
- No information avaliable
Cetrotide Chemical_Formula
No information avaliable
Cetrotide RX_link
http://www.rxlist.com/cgi/generic2/cetrorelix.htm
Cetrotide fda sheet
Cetrotide msds (material safety sheet)
Cetrotide Synthesis Reference
No information avaliable
Cetrotide Molecular Weight
1431.06 g/mol
Cetrotide Melting Point
No information avaliable
Cetrotide H2O Solubility
No information avaliable
Cetrotide State
Solid
Cetrotide LogP
No information avaliable
Cetrotide Dosage Forms
Powder for solution
Cetrotide Indication
For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.
Cetrotide Pharmacology
Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.
Cetrotide Absorption
Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.
Cetrotide side effects and Toxicity
No information avaliable
Cetrotide Patient Information
Cetrotide Organisms Affected
Humans and other mammals
