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Fosamax Brand names, Fosamax Analogs

Fosamax Brand Names Mixture

  • No information avaliable

Fosamax Chemical_Formula


Fosamax RX_link

Fosamax fda sheet

Fosamax FDA

Fosamax msds (material safety sheet)

Fosamax MSDS

Fosamax Synthesis Reference

M. I. Kabachnik et al., Bull. Acad. Sci. USSR,.27, 374 (1978)

Fosamax Molecular Weight

249.096 g/mol

Fosamax Melting Point

233 - 235 oC

Fosamax H2O Solubility


Fosamax State


Fosamax LogP


Fosamax Dosage Forms

Tablets (6.53, 13.05, 45.68, 52.21 or 91.37 mg of alendronate monosodium salt trihydrate)

Fosamax Indication

For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.

Fosamax Pharmacology

Alendronate, a second-generation bisphosphonate is the first member of a group of drugs which strengthens bone. Alendronate is used to reduce hypercalcemia in tumor-induced bone disease, to treat corticosteroid-induced osteoporosis and Paget's disease, and to prevent osteoporosis in postmenopausal women.

Fosamax Absorption

Relative to an intravenous (IV) reference dose, the mean oral bioavailability of alendronate in women was 0.7% for doses ranging from 5 to 40 mg when administered after an overnight fast and two hours before a standardized breakfast. Oral bioavailability of the 10 mg tablet in men (0.59%) was similar to that in women (0.78%) when administered after an overnight fast and 2 hours before breakfast.

Fosamax side effects and Toxicity

Alendronate can damage the esophagus both by toxicity from the medication itself and by nonspecific irritation secondary to contact between the pill and the esophageal mucosa, similar to other cases of "pill esophagitis."

Fosamax Patient Information

Fosamax Organisms Affected

Humans and other mammals