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Adronat Brand names, Adronat Analogs

Adronat Brand Names Mixture

  • No information avaliable

Adronat Chemical_Formula


Adronat RX_link

Adronat fda sheet

Adronat FDA

Adronat msds (material safety sheet)

Adronat MSDS

Adronat Synthesis Reference

M. I. Kabachnik et al., Bull. Acad. Sci. USSR,.27, 374 (1978)

Adronat Molecular Weight

249.096 g/mol

Adronat Melting Point

233 - 235 oC

Adronat H2O Solubility


Adronat State


Adronat LogP


Adronat Dosage Forms

Tablets (6.53, 13.05, 45.68, 52.21 or 91.37 mg of alendronate monosodium salt trihydrate)

Adronat Indication

For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.

Adronat Pharmacology

Alendronate, a second-generation bisphosphonate is the first member of a group of drugs which strengthens bone. Alendronate is used to reduce hypercalcemia in tumor-induced bone disease, to treat corticosteroid-induced osteoporosis and Paget's disease, and to prevent osteoporosis in postmenopausal women.

Adronat Absorption

Relative to an intravenous (IV) reference dose, the mean oral bioavailability of alendronate in women was 0.7% for doses ranging from 5 to 40 mg when administered after an overnight fast and two hours before a standardized breakfast. Oral bioavailability of the 10 mg tablet in men (0.59%) was similar to that in women (0.78%) when administered after an overnight fast and 2 hours before breakfast.

Adronat side effects and Toxicity

Alendronate can damage the esophagus both by toxicity from the medication itself and by nonspecific irritation secondary to contact between the pill and the esophageal mucosa, similar to other cases of "pill esophagitis."

Adronat Patient Information

Adronat Organisms Affected

Humans and other mammals