Alendronic acid en es it fr

Alendronic acid Brand names, Alendronic acid Analogs

Alendronic acid Brand Names Mixture

  • No information avaliable

Alendronic acid Chemical_Formula


Alendronic acid RX_link

Alendronic acid fda sheet

Alendronic_acid FDA

Alendronic acid msds (material safety sheet)

Alendronic_acid MSDS

Alendronic acid Synthesis Reference

M. I. Kabachnik et al., Bull. Acad. Sci. USSR,.27, 374 (1978)

Alendronic acid Molecular Weight

249.096 g/mol

Alendronic acid Melting Point

233 - 235 oC

Alendronic acid H2O Solubility


Alendronic acid State


Alendronic acid LogP


Alendronic acid Dosage Forms

Tablets (6.53, 13.05, 45.68, 52.21 or 91.37 mg of alendronate monosodium salt trihydrate)

Alendronic acid Indication

For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.

Alendronic acid Pharmacology

Alendronate, a second-generation bisphosphonate is the first member of a group of drugs which strengthens bone. Alendronate is used to reduce hypercalcemia in tumor-induced bone disease, to treat corticosteroid-induced osteoporosis and Paget's disease, and to prevent osteoporosis in postmenopausal women.

Alendronic acid Absorption

Relative to an intravenous (IV) reference dose, the mean oral bioavailability of alendronate in women was 0.7% for doses ranging from 5 to 40 mg when administered after an overnight fast and two hours before a standardized breakfast. Oral bioavailability of the 10 mg tablet in men (0.59%) was similar to that in women (0.78%) when administered after an overnight fast and 2 hours before breakfast.

Alendronic acid side effects and Toxicity

Alendronate can damage the esophagus both by toxicity from the medication itself and by nonspecific irritation secondary to contact between the pill and the esophageal mucosa, similar to other cases of "pill esophagitis."

Alendronic acid Patient Information

Alendronic acid Organisms Affected

Humans and other mammals