Alendronate Sodium en es it fr

Alendronate Sodium Brand names, Alendronate Sodium Analogs

Alendronate Sodium Brand Names Mixture

  • No information avaliable

Alendronate Sodium Chemical_Formula

C4H13NO7P2

Alendronate Sodium RX_link

http://www.rxlist.com/cgi/generic/alendron.htm

Alendronate Sodium fda sheet

Alendronate_Sodium FDA

Alendronate Sodium msds (material safety sheet)

Alendronate_Sodium MSDS

Alendronate Sodium Synthesis Reference

M. I. Kabachnik et al., Bull. Acad. Sci. USSR,.27, 374 (1978)

Alendronate Sodium Molecular Weight

249.096 g/mol

Alendronate Sodium Melting Point

233 - 235 oC

Alendronate Sodium H2O Solubility

1mg/L

Alendronate Sodium State

Solid

Alendronate Sodium LogP

-3.198

Alendronate Sodium Dosage Forms

Tablets (6.53, 13.05, 45.68, 52.21 or 91.37 mg of alendronate monosodium salt trihydrate)

Alendronate Sodium Indication

For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.

Alendronate Sodium Pharmacology

Alendronate, a second-generation bisphosphonate is the first member of a group of drugs which strengthens bone. Alendronate is used to reduce hypercalcemia in tumor-induced bone disease, to treat corticosteroid-induced osteoporosis and Paget's disease, and to prevent osteoporosis in postmenopausal women.

Alendronate Sodium Absorption

Relative to an intravenous (IV) reference dose, the mean oral bioavailability of alendronate in women was 0.7% for doses ranging from 5 to 40 mg when administered after an overnight fast and two hours before a standardized breakfast. Oral bioavailability of the 10 mg tablet in men (0.59%) was similar to that in women (0.78%) when administered after an overnight fast and 2 hours before breakfast.

Alendronate Sodium side effects and Toxicity

Alendronate can damage the esophagus both by toxicity from the medication itself and by nonspecific irritation secondary to contact between the pill and the esophageal mucosa, similar to other cases of "pill esophagitis."

Alendronate Sodium Patient Information

Alendronate Sodium Organisms Affected

Humans and other mammals