Entecavir
Entecavir Brand names, Entecavir Analogs
Entecavir Brand Names Mixture
- No information avaliable
Entecavir Chemical_Formula
C12H15N5O3
Entecavir RX_link
http://www.rxlist.com/cgi/generic4/baraclude.htm
Entecavir fda sheet
Entecavir msds (material safety sheet)
Entecavir Synthesis Reference
No information avaliable
Entecavir Molecular Weight
277.279 g/mol
Entecavir Melting Point
No information avaliable
Entecavir H2O Solubility
Slightly soluble (2.4 mg/mL at pH 7.9, 25oC)
Entecavir State
Solid
Entecavir LogP
No information avaliable
Entecavir Dosage Forms
Film-coated tablets for oral administration (0.5 mg, 1 mg); Oral solution (0.05 mg/mL)
Entecavir Indication
For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Entecavir Pharmacology
Entecavir is a guanosine nucleoside analogue with selective activity against hepatitis B virus (HBV). It is designed to selectively inhibit the Hepatitis B virus, blocking all three steps in the replication process. Entecavir is more efficient than an older Hepatitis B drug, lamivudine.
Entecavir Absorption
Absorption Following oral administration in healthy subjects, entecavir peak plasma concentrations occurred between 0.5 and 1.5 hours. In healthy subjects, the bioavailability of the tablet is 100% relative to the oral solution.
Entecavir side effects and Toxicity
No information avaliable
Entecavir Patient Information
Entecavir Organisms Affected
Hepatitis B
