Spectazole cream
Brand names,
Spectazole cream
Analogs
Spectazole cream
Brand Names Mixture
Spectazole cream
Chemical_Formula
C12H15N5O3
Spectazole cream
RX_link
http://www.rxlist.com/cgi/generic4/baraclude.htm
Spectazole cream
fda sheet
Spectazole cream
msds (material safety sheet)
Spectazole cream
Synthesis Reference
No information avaliable
Spectazole cream
Molecular Weight
277.279 g/mol
Spectazole cream
Melting Point
No information avaliable
Spectazole cream
H2O Solubility
Slightly soluble (2.4 mg/mL at pH 7.9, 25oC)
Spectazole cream
State
Solid
Spectazole cream
LogP
No information avaliable
Spectazole cream
Dosage Forms
Film-coated tablets for oral administration (0.5 mg, 1 mg); Oral solution (0.05 mg/mL)
Spectazole cream
Indication
For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Spectazole cream
Pharmacology
Entecavir is a guanosine nucleoside analogue with selective activity against hepatitis B virus (HBV). It is designed to selectively inhibit the Hepatitis B virus, blocking all three steps in the replication process. Entecavir is more efficient than an older Hepatitis B drug, lamivudine.
Spectazole cream
Absorption
Absorption Following oral administration in healthy subjects, entecavir peak plasma concentrations occurred between 0.5 and 1.5 hours. In healthy subjects, the bioavailability of the tablet is 100% relative to the oral solution.
Spectazole cream
side effects and Toxicity
No information avaliable
Spectazole cream
Patient Information
Spectazole cream
Organisms Affected
Hepatitis B