Ecostatin
Brand names,
Ecostatin
Analogs
Ecostatin
Brand Names Mixture
Ecostatin
Chemical_Formula
C12H15N5O3
Ecostatin
RX_link
http://www.rxlist.com/cgi/generic4/baraclude.htm
Ecostatin
fda sheet
Ecostatin
msds (material safety sheet)
Ecostatin
Synthesis Reference
No information avaliable
Ecostatin
Molecular Weight
277.279 g/mol
Ecostatin
Melting Point
No information avaliable
Ecostatin
H2O Solubility
Slightly soluble (2.4 mg/mL at pH 7.9, 25oC)
Ecostatin
State
Solid
Ecostatin
LogP
No information avaliable
Ecostatin
Dosage Forms
Film-coated tablets for oral administration (0.5 mg, 1 mg); Oral solution (0.05 mg/mL)
Ecostatin
Indication
For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Ecostatin
Pharmacology
Entecavir is a guanosine nucleoside analogue with selective activity against hepatitis B virus (HBV). It is designed to selectively inhibit the Hepatitis B virus, blocking all three steps in the replication process. Entecavir is more efficient than an older Hepatitis B drug, lamivudine.
Ecostatin
Absorption
Absorption Following oral administration in healthy subjects, entecavir peak plasma concentrations occurred between 0.5 and 1.5 hours. In healthy subjects, the bioavailability of the tablet is 100% relative to the oral solution.
Ecostatin
side effects and Toxicity
No information avaliable
Ecostatin
Patient Information
Ecostatin
Organisms Affected
Hepatitis B