Econazole Nitrate
Brand names,
Econazole Nitrate
Analogs
Econazole Nitrate
Brand Names Mixture
Econazole Nitrate
Chemical_Formula
C12H15N5O3
Econazole Nitrate
RX_link
http://www.rxlist.com/cgi/generic4/baraclude.htm
Econazole Nitrate
fda sheet
Econazole Nitrate
msds (material safety sheet)
Econazole Nitrate
Synthesis Reference
No information avaliable
Econazole Nitrate
Molecular Weight
277.279 g/mol
Econazole Nitrate
Melting Point
No information avaliable
Econazole Nitrate
H2O Solubility
Slightly soluble (2.4 mg/mL at pH 7.9, 25oC)
Econazole Nitrate
State
Solid
Econazole Nitrate
LogP
No information avaliable
Econazole Nitrate
Dosage Forms
Film-coated tablets for oral administration (0.5 mg, 1 mg); Oral solution (0.05 mg/mL)
Econazole Nitrate
Indication
For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Econazole Nitrate
Pharmacology
Entecavir is a guanosine nucleoside analogue with selective activity against hepatitis B virus (HBV). It is designed to selectively inhibit the Hepatitis B virus, blocking all three steps in the replication process. Entecavir is more efficient than an older Hepatitis B drug, lamivudine.
Econazole Nitrate
Absorption
Absorption Following oral administration in healthy subjects, entecavir peak plasma concentrations occurred between 0.5 and 1.5 hours. In healthy subjects, the bioavailability of the tablet is 100% relative to the oral solution.
Econazole Nitrate
side effects and Toxicity
No information avaliable
Econazole Nitrate
Patient Information
Econazole Nitrate
Organisms Affected
Hepatitis B