Pevaryl
Pevaryl Brand names, Pevaryl Analogs
Pevaryl Brand Names Mixture
- No information avaliable
Pevaryl Chemical_Formula
C12H15N5O3
Pevaryl RX_link
http://www.rxlist.com/cgi/generic4/baraclude.htm
Pevaryl fda sheet
Pevaryl msds (material safety sheet)
Pevaryl Synthesis Reference
No information avaliable
Pevaryl Molecular Weight
277.279 g/mol
Pevaryl Melting Point
No information avaliable
Pevaryl H2O Solubility
Slightly soluble (2.4 mg/mL at pH 7.9, 25oC)
Pevaryl State
Solid
Pevaryl LogP
No information avaliable
Pevaryl Dosage Forms
Film-coated tablets for oral administration (0.5 mg, 1 mg); Oral solution (0.05 mg/mL)
Pevaryl Indication
For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Pevaryl Pharmacology
Entecavir is a guanosine nucleoside analogue with selective activity against hepatitis B virus (HBV). It is designed to selectively inhibit the Hepatitis B virus, blocking all three steps in the replication process. Entecavir is more efficient than an older Hepatitis B drug, lamivudine.
Pevaryl Absorption
Absorption Following oral administration in healthy subjects, entecavir peak plasma concentrations occurred between 0.5 and 1.5 hours. In healthy subjects, the bioavailability of the tablet is 100% relative to the oral solution.
Pevaryl side effects and Toxicity
No information avaliable
Pevaryl Patient Information
Pevaryl Organisms Affected
Hepatitis B
