Dihydroergotamine methanesulfonate
Brand names,
Dihydroergotamine methanesulfonate
Analogs
Dihydroergotamine methanesulfonate
Brand Names Mixture
Dihydroergotamine methanesulfonate
Chemical_Formula
C33H37N5O5
Dihydroergotamine methanesulfonate
RX_link
http://www.rxlist.com/cgi/generic2/dihyergmes.htm
Dihydroergotamine methanesulfonate
fda sheet
Dihydroergotamine methanesulfonate
msds (material safety sheet)
Dihydroergotamine methanesulfonate
Synthesis Reference
No information avaliable
Dihydroergotamine methanesulfonate
Molecular Weight
583.678 g/mol
Dihydroergotamine methanesulfonate
Melting Point
No information avaliable
Dihydroergotamine methanesulfonate
H2O Solubility
No information avaliable
Dihydroergotamine methanesulfonate
State
Solid
Dihydroergotamine methanesulfonate
LogP
No information avaliable
Dihydroergotamine methanesulfonate
Dosage Forms
Liquid
Dihydroergotamine methanesulfonate
Indication
For the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes.
Dihydroergotamine methanesulfonate
Pharmacology
Dihydroergotamine is indicated for the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. Dihydroergotamine binds with high affinity to 5-HT1Da and 5-HT1Db receptors. It also binds with high affinity to serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors, noradrenaline a2A, a2B and a receptors, and dopamine D2L and D3 receptors. The therapeutic activity of Dihydroergotamine in migraine is generally attributed to the agonist effect at 5-HT1D receptors.
Dihydroergotamine methanesulfonate
Absorption
Interpatient variable and may be dependent on the administration technique
Dihydroergotamine methanesulfonate
side effects and Toxicity
Side effects include abdominal pain, abnormal speech, coma, confusion, convulsions, hallucinations, increase and/or decrease in blood pressure, nausea, numbness, tingling, pain, and a bluish color of your fingersand toes, slowed breathing, vomiting
Dihydroergotamine methanesulfonate
Patient Information
PATIENT INFORMATIOn
Follow the link below to get detailed information before taking D.H.E. 45� (dihydroergotamine mesylate) Injection.
http://www.rxlist.com/cgi/generic2/dihyergmes_pi.htm
Dihydroergotamine methanesulfonate
Organisms Affected
Humans and other mammals