Verladyn
Brand names,
Verladyn
Analogs
Verladyn
Brand Names Mixture
Verladyn
Chemical_Formula
C33H37N5O5
Verladyn
RX_link
http://www.rxlist.com/cgi/generic2/dihyergmes.htm
Verladyn
fda sheet
Verladyn
msds (material safety sheet)
Verladyn
Synthesis Reference
No information avaliable
Verladyn
Molecular Weight
583.678 g/mol
Verladyn
Melting Point
No information avaliable
Verladyn
H2O Solubility
No information avaliable
Verladyn
State
Solid
Verladyn
LogP
No information avaliable
Verladyn
Dosage Forms
Liquid
Verladyn
Indication
For the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes.
Verladyn
Pharmacology
Dihydroergotamine is indicated for the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. Dihydroergotamine binds with high affinity to 5-HT1Da and 5-HT1Db receptors. It also binds with high affinity to serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors, noradrenaline a2A, a2B and a receptors, and dopamine D2L and D3 receptors. The therapeutic activity of Dihydroergotamine in migraine is generally attributed to the agonist effect at 5-HT1D receptors.
Verladyn
Absorption
Interpatient variable and may be dependent on the administration technique
Verladyn
side effects and Toxicity
Side effects include abdominal pain, abnormal speech, coma, confusion, convulsions, hallucinations, increase and/or decrease in blood pressure, nausea, numbness, tingling, pain, and a bluish color of your fingersand toes, slowed breathing, vomiting
Verladyn
Patient Information
PATIENT INFORMATIOn
Follow the link below to get detailed information before taking D.H.E. 45� (dihydroergotamine mesylate) Injection.
http://www.rxlist.com/cgi/generic2/dihyergmes_pi.htm
Verladyn
Organisms Affected
Humans and other mammals