Dihydroergotamine monomethanesulfonate
Brand names,
Dihydroergotamine monomethanesulfonate
Analogs
Dihydroergotamine monomethanesulfonate
Brand Names Mixture
Dihydroergotamine monomethanesulfonate
Chemical_Formula
C33H37N5O5
Dihydroergotamine monomethanesulfonate
RX_link
http://www.rxlist.com/cgi/generic2/dihyergmes.htm
Dihydroergotamine monomethanesulfonate
fda sheet
Dihydroergotamine monomethanesulfonate
msds (material safety sheet)
Dihydroergotamine monomethanesulfonate
Synthesis Reference
No information avaliable
Dihydroergotamine monomethanesulfonate
Molecular Weight
583.678 g/mol
Dihydroergotamine monomethanesulfonate
Melting Point
No information avaliable
Dihydroergotamine monomethanesulfonate
H2O Solubility
No information avaliable
Dihydroergotamine monomethanesulfonate
State
Solid
Dihydroergotamine monomethanesulfonate
LogP
No information avaliable
Dihydroergotamine monomethanesulfonate
Dosage Forms
Liquid
Dihydroergotamine monomethanesulfonate
Indication
For the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes.
Dihydroergotamine monomethanesulfonate
Pharmacology
Dihydroergotamine is indicated for the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. Dihydroergotamine binds with high affinity to 5-HT1Da and 5-HT1Db receptors. It also binds with high affinity to serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors, noradrenaline a2A, a2B and a receptors, and dopamine D2L and D3 receptors. The therapeutic activity of Dihydroergotamine in migraine is generally attributed to the agonist effect at 5-HT1D receptors.
Dihydroergotamine monomethanesulfonate
Absorption
Interpatient variable and may be dependent on the administration technique
Dihydroergotamine monomethanesulfonate
side effects and Toxicity
Side effects include abdominal pain, abnormal speech, coma, confusion, convulsions, hallucinations, increase and/or decrease in blood pressure, nausea, numbness, tingling, pain, and a bluish color of your fingersand toes, slowed breathing, vomiting
Dihydroergotamine monomethanesulfonate
Patient Information
PATIENT INFORMATIOn
Follow the link below to get detailed information before taking D.H.E. 45� (dihydroergotamine mesylate) Injection.
http://www.rxlist.com/cgi/generic2/dihyergmes_pi.htm
Dihydroergotamine monomethanesulfonate
Organisms Affected
Humans and other mammals