Dextromethorphan
Brand names,
Dextromethorphan
Analogs
Dextromethorphan
Brand Names Mixture
Dextromethorphan
Chemical_Formula
C18H25NO
Dextromethorphan
RX_link
No information avaliable
Dextromethorphan
fda sheet
Dextromethorphan
msds (material safety sheet)
Dextromethorphan
Synthesis Reference
No information avaliable
Dextromethorphan
Molecular Weight
271.397 g/mol
Dextromethorphan
Melting Point
No information avaliable
Dextromethorphan
H2O Solubility
74.7 mg/L
Dextromethorphan
State
Solid
Dextromethorphan
LogP
4.323
Dextromethorphan
Dosage Forms
Capsule; Liquid; Lozenge; Syrup; Tablet
Dextromethorphan
Indication
For treatment and relief of dry cough.
Dextromethorphan
Pharmacology
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Dextromethorphan
Absorption
Rapidly absorbed from the gastrointestinal tract.
Dextromethorphan
side effects and Toxicity
No information avaliable
Dextromethorphan
Patient Information
No information avaliable
Dextromethorphan
Organisms Affected
Humans and other mammals