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Biperiden Brand names, Biperiden Analogs

Biperiden Brand Names Mixture

  • No information avaliable

Biperiden Chemical_Formula

C21H29NO

Biperiden RX_link

http://www.rxlist.com/cgi/generic2/biperiden.htm

Biperiden fda sheet

Biperiden msds (material safety sheet)

Biperiden Synthesis Reference

No information avaliable

Biperiden Molecular Weight

311.461 g/mol

Biperiden Melting Point

114 oC

Biperiden H2O Solubility

25.1 mg/L

Biperiden State

Solid

Biperiden LogP

3.85

Biperiden Dosage Forms

Tablet

Biperiden Indication

For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.

Biperiden Pharmacology

Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control.

Biperiden Absorption

87% bioavailability

Biperiden side effects and Toxicity

LD50=760 mg/kg (Orally in rats). Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Biperiden Patient Information

No information avaliable

Biperiden Organisms Affected

Humans and other mammals