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Beperiden Brand names, Beperiden Analogs

Beperiden Brand Names Mixture

  • No information avaliable

Beperiden Chemical_Formula

C21H29NO

Beperiden RX_link

http://www.rxlist.com/cgi/generic2/biperiden.htm

Beperiden fda sheet

Beperiden msds (material safety sheet)

Beperiden Synthesis Reference

No information avaliable

Beperiden Molecular Weight

311.461 g/mol

Beperiden Melting Point

114 oC

Beperiden H2O Solubility

25.1 mg/L

Beperiden State

Solid

Beperiden LogP

3.85

Beperiden Dosage Forms

Tablet

Beperiden Indication

For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.

Beperiden Pharmacology

Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control.

Beperiden Absorption

87% bioavailability

Beperiden side effects and Toxicity

LD50=760 mg/kg (Orally in rats). Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Beperiden Patient Information

No information avaliable

Beperiden Organisms Affected

Humans and other mammals