Biperidene [Inn-French] en es it fr

Biperidene [Inn-French] Brand names, Biperidene [Inn-French] Analogs

Biperidene [Inn-French] Brand Names Mixture

  • No information avaliable

Biperidene [Inn-French] Chemical_Formula

C21H29NO

Biperidene [Inn-French] RX_link

http://www.rxlist.com/cgi/generic2/biperiden.htm

Biperidene [Inn-French] fda sheet

Biperidene [Inn-French] msds (material safety sheet)

Biperidene [Inn-French] Synthesis Reference

No information avaliable

Biperidene [Inn-French] Molecular Weight

311.461 g/mol

Biperidene [Inn-French] Melting Point

114 oC

Biperidene [Inn-French] H2O Solubility

25.1 mg/L

Biperidene [Inn-French] State

Solid

Biperidene [Inn-French] LogP

3.85

Biperidene [Inn-French] Dosage Forms

Tablet

Biperidene [Inn-French] Indication

For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.

Biperidene [Inn-French] Pharmacology

Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control.

Biperidene [Inn-French] Absorption

87% bioavailability

Biperidene [Inn-French] side effects and Toxicity

LD50=760 mg/kg (Orally in rats). Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Biperidene [Inn-French] Patient Information

No information avaliable

Biperidene [Inn-French] Organisms Affected

Humans and other mammals