Akineton en es it fr

Akineton Brand names, Akineton Analogs

Akineton Brand Names Mixture

  • No information avaliable

Akineton Chemical_Formula

C21H29NO

Akineton RX_link

http://www.rxlist.com/cgi/generic2/biperiden.htm

Akineton fda sheet

Akineton msds (material safety sheet)

Akineton Synthesis Reference

No information avaliable

Akineton Molecular Weight

311.461 g/mol

Akineton Melting Point

114 oC

Akineton H2O Solubility

25.1 mg/L

Akineton State

Solid

Akineton LogP

3.85

Akineton Dosage Forms

Tablet

Akineton Indication

For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.

Akineton Pharmacology

Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control.

Akineton Absorption

87% bioavailability

Akineton side effects and Toxicity

LD50=760 mg/kg (Orally in rats). Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Akineton Patient Information

No information avaliable

Akineton Organisms Affected

Humans and other mammals