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Alendronate Brand names, Alendronate Analogs

Alendronate Brand Names Mixture

  • No information avaliable

Alendronate Chemical_Formula


Alendronate RX_link

Alendronate fda sheet

Alendronate FDA

Alendronate msds (material safety sheet)

Alendronate MSDS

Alendronate Synthesis Reference

M. I. Kabachnik et al., Bull. Acad. Sci. USSR,.27, 374 (1978)

Alendronate Molecular Weight

249.096 g/mol

Alendronate Melting Point

233 - 235 oC

Alendronate H2O Solubility


Alendronate State


Alendronate LogP


Alendronate Dosage Forms

Tablets (6.53, 13.05, 45.68, 52.21 or 91.37 mg of alendronate monosodium salt trihydrate)

Alendronate Indication

For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.

Alendronate Pharmacology

Alendronate, a second-generation bisphosphonate is the first member of a group of drugs which strengthens bone. Alendronate is used to reduce hypercalcemia in tumor-induced bone disease, to treat corticosteroid-induced osteoporosis and Paget's disease, and to prevent osteoporosis in postmenopausal women.

Alendronate Absorption

Relative to an intravenous (IV) reference dose, the mean oral bioavailability of alendronate in women was 0.7% for doses ranging from 5 to 40 mg when administered after an overnight fast and two hours before a standardized breakfast. Oral bioavailability of the 10 mg tablet in men (0.59%) was similar to that in women (0.78%) when administered after an overnight fast and 2 hours before breakfast.

Alendronate side effects and Toxicity

Alendronate can damage the esophagus both by toxicity from the medication itself and by nonspecific irritation secondary to contact between the pill and the esophageal mucosa, similar to other cases of "pill esophagitis."

Alendronate Patient Information

Alendronate Organisms Affected

Humans and other mammals