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AKPro Brand names, AKPro Analogs

AKPro Brand Names Mixture

  • No information avaliable

AKPro Chemical_Formula


AKPro RX_link


AKPro fda sheet


AKPro msds (material safety sheet)


AKPro Synthesis Reference

No information avaliable

AKPro Molecular Weight

351.437 g/mol

AKPro Melting Point

No information avaliable

AKPro H2O Solubility

Freely soluble as HCl salt

AKPro State


AKPro LogP


AKPro Dosage Forms

Drops; Liquid; Solution

AKPro Indication

Used as initial therapy for the control of intraocular pressure in chronic open-angle glaucoma.

AKPro Pharmacology

Dipivefrin is a member of a class of drugs known as prodrugs. Prodrugs are usually not active in themselves and require biotransformation to the parent compound before therapeutic activity is seen. These modifications are undertaken to enhance absorption, decrease side effects and enhance stability and comfort, thus making the parent compound a more useful drug. Enhanced absorption makes the prodrug a more efficient delivery system for the parent drug because less drug will be needed to produce the desired therapeutic response. Dipivefrin is a prodrug of epinephrine formed by the diesterification of epinephrine and pivalic acid. The addition of pivaloyl groups to the epinephrine molecule enhances its lipophilic character and, as a consequence, its penetration into the anterior chamber.

AKPro Absorption

Well absorbed following occular administration.

AKPro side effects and Toxicity

Oral LD50 in rat is 183 mg/kg.

AKPro Patient Information

No information avaliable

AKPro Organisms Affected

Humans and other mammals