Dipivefrin HCL en es it fr

Dipivefrin HCL Brand names, Dipivefrin HCL Analogs

Dipivefrin HCL Brand Names Mixture

  • No information avaliable

Dipivefrin HCL Chemical_Formula


Dipivefrin HCL RX_link


Dipivefrin HCL fda sheet

Dipivefrin_HCL FDA

Dipivefrin HCL msds (material safety sheet)

Dipivefrin_HCL MSDS

Dipivefrin HCL Synthesis Reference

No information avaliable

Dipivefrin HCL Molecular Weight

351.437 g/mol

Dipivefrin HCL Melting Point

No information avaliable

Dipivefrin HCL H2O Solubility

Freely soluble as HCl salt

Dipivefrin HCL State


Dipivefrin HCL LogP


Dipivefrin HCL Dosage Forms

Drops; Liquid; Solution

Dipivefrin HCL Indication

Used as initial therapy for the control of intraocular pressure in chronic open-angle glaucoma.

Dipivefrin HCL Pharmacology

Dipivefrin is a member of a class of drugs known as prodrugs. Prodrugs are usually not active in themselves and require biotransformation to the parent compound before therapeutic activity is seen. These modifications are undertaken to enhance absorption, decrease side effects and enhance stability and comfort, thus making the parent compound a more useful drug. Enhanced absorption makes the prodrug a more efficient delivery system for the parent drug because less drug will be needed to produce the desired therapeutic response. Dipivefrin is a prodrug of epinephrine formed by the diesterification of epinephrine and pivalic acid. The addition of pivaloyl groups to the epinephrine molecule enhances its lipophilic character and, as a consequence, its penetration into the anterior chamber.

Dipivefrin HCL Absorption

Well absorbed following occular administration.

Dipivefrin HCL side effects and Toxicity

Oral LD50 in rat is 183 mg/kg.

Dipivefrin HCL Patient Information

No information avaliable

Dipivefrin HCL Organisms Affected

Humans and other mammals