Ophtho-Dipivefrin en es it fr

Ophtho-Dipivefrin Brand names, Ophtho-Dipivefrin Analogs

Ophtho-Dipivefrin Brand Names Mixture

  • No information avaliable

Ophtho-Dipivefrin Chemical_Formula


Ophtho-Dipivefrin RX_link


Ophtho-Dipivefrin fda sheet

Ophtho-Dipivefrin FDA

Ophtho-Dipivefrin msds (material safety sheet)

Ophtho-Dipivefrin MSDS

Ophtho-Dipivefrin Synthesis Reference

No information avaliable

Ophtho-Dipivefrin Molecular Weight

351.437 g/mol

Ophtho-Dipivefrin Melting Point

No information avaliable

Ophtho-Dipivefrin H2O Solubility

Freely soluble as HCl salt

Ophtho-Dipivefrin State


Ophtho-Dipivefrin LogP


Ophtho-Dipivefrin Dosage Forms

Drops; Liquid; Solution

Ophtho-Dipivefrin Indication

Used as initial therapy for the control of intraocular pressure in chronic open-angle glaucoma.

Ophtho-Dipivefrin Pharmacology

Dipivefrin is a member of a class of drugs known as prodrugs. Prodrugs are usually not active in themselves and require biotransformation to the parent compound before therapeutic activity is seen. These modifications are undertaken to enhance absorption, decrease side effects and enhance stability and comfort, thus making the parent compound a more useful drug. Enhanced absorption makes the prodrug a more efficient delivery system for the parent drug because less drug will be needed to produce the desired therapeutic response. Dipivefrin is a prodrug of epinephrine formed by the diesterification of epinephrine and pivalic acid. The addition of pivaloyl groups to the epinephrine molecule enhances its lipophilic character and, as a consequence, its penetration into the anterior chamber.

Ophtho-Dipivefrin Absorption

Well absorbed following occular administration.

Ophtho-Dipivefrin side effects and Toxicity

Oral LD50 in rat is 183 mg/kg.

Ophtho-Dipivefrin Patient Information

No information avaliable

Ophtho-Dipivefrin Organisms Affected

Humans and other mammals