Sporostatin xan
Category
Sporostatin xan Brand names, Sporostatin xan Analogs
Sporostatin xan Brand Names Mixture
Sporostatin xan Chemical_Formula
C17H17ClO6
Sporostatin xan RX_link
http://www.rxlist.com/cgi/generic3/griseofulvin.htm
Sporostatin xan fda sheet
Sporostatin xan msds (material safety sheet)
Sporostatin xan Synthesis Reference
No information avaliable
Sporostatin xan Molecular Weight
352.766 g/mol
Sporostatin xan Melting Point
220 oC
Sporostatin xan H2O Solubility
8.64 mg/L
Sporostatin xan State
Solid
Sporostatin xan LogP
2.15
Sporostatin xan Dosage Forms
Powder; Tablet
Sporostatin xan Indication
For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.
Sporostatin xan Pharmacology
Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.
Sporostatin xan Absorption
Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.
Sporostatin xan side effects and Toxicity
Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions
Sporostatin xan Patient Information
Sporostatin xan Organisms Affected
Yeast and other Trichophyton or Microsporum fungi