Grysio en es it fr

Grysio Brand names, Grysio Analogs

Grysio Brand Names Mixture

  • No information avaliable

Grysio Chemical_Formula

C17H17ClO6

Grysio RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Grysio fda sheet

Grysio msds (material safety sheet)

Grysio MSDS

Grysio Synthesis Reference

No information avaliable

Grysio Molecular Weight

352.766 g/mol

Grysio Melting Point

220 oC

Grysio H2O Solubility

8.64 mg/L

Grysio State

Solid

Grysio LogP

2.15

Grysio Dosage Forms

Powder; Tablet

Grysio Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Grysio Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Grysio Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Grysio side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Grysio Patient Information

Grysio Organisms Affected

Yeast and other Trichophyton or Microsporum fungi