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Fulcin
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Fulcin Brand names, Fulcin Analogs

Fulcin Brand Names Mixture

  • No information avaliable

Fulcin Chemical_Formula

C17H17ClO6

Fulcin RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Fulcin fda sheet

Fulcin msds (material safety sheet)

Fulcin MSDS

Fulcin Synthesis Reference

No information avaliable

Fulcin Molecular Weight

352.766 g/mol

Fulcin Melting Point

220 oC

Fulcin H2O Solubility

8.64 mg/L

Fulcin State

Solid

Fulcin LogP

2.15

Fulcin Dosage Forms

Powder; Tablet

Fulcin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Fulcin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Fulcin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Fulcin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Fulcin Patient Information

Fulcin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi