Fulcine en es it fr

Fulcine Brand names, Fulcine Analogs

Fulcine Brand Names Mixture

  • No information avaliable

Fulcine Chemical_Formula

C17H17ClO6

Fulcine RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Fulcine fda sheet

Fulcine msds (material safety sheet)

Fulcine MSDS

Fulcine Synthesis Reference

No information avaliable

Fulcine Molecular Weight

352.766 g/mol

Fulcine Melting Point

220 oC

Fulcine H2O Solubility

8.64 mg/L

Fulcine State

Solid

Fulcine LogP

2.15

Fulcine Dosage Forms

Powder; Tablet

Fulcine Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Fulcine Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Fulcine Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Fulcine side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Fulcine Patient Information

Fulcine Organisms Affected

Yeast and other Trichophyton or Microsporum fungi