Grisactin Brand names, Grisactin Analogs
Grisactin Brand Names Mixture
Grisactin fda sheet
Grisactin msds (material safety sheet)
Grisactin Synthesis Reference
No information avaliable
Grisactin Molecular Weight
Grisactin Melting Point
Grisactin H2O Solubility
Grisactin Dosage Forms
For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.
Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.
Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.
Grisactin side effects and Toxicity
Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions
Grisactin Patient Information
Grisactin Organisms Affected
Yeast and other Trichophyton or Microsporum fungi