Metalcaptase
Category
Metalcaptase Brand names, Metalcaptase Analogs
Metalcaptase Brand Names Mixture
No information avaliable
Metalcaptase Chemical_Formula
C5H11NO2S
Metalcaptase RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Metalcaptase fda sheet
Metalcaptase msds (material safety sheet)
Metalcaptase Synthesis Reference
No information avaliable
Metalcaptase Molecular Weight
149.212 g/mol
Metalcaptase Melting Point
198.5 oC
Metalcaptase H2O Solubility
1.11E+005 mg/L
Metalcaptase State
Solid
Metalcaptase LogP
-2.09
Metalcaptase Dosage Forms
Capsule; Tablet
Metalcaptase Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Metalcaptase Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Metalcaptase Absorption
rapidly but incompletely
Metalcaptase Toxicity
No information avaliable
Metalcaptase Patient Information
No information avaliable
Metalcaptase Organisms Affected
Humans and other mammals
