HiFD`JxPBLbdTljjZDp@

Category

HiFD`JxPBLbdTljjZDp@




Useful info

HiFD`JxPBLbdTljjZDp@ Brand names, HiFD`JxPBLbdTljjZDp@ Analogs

HiFD`JxPBLbdTljjZDp@ Brand Names Mixture

  • No information avaliable

    • HiFD`JxPBLbdTljjZDp@ Chemical_Formula

    C5H11NO2S

    HiFD`JxPBLbdTljjZDp@ RX_link

    http://www.rxlist.com/cgi/generic3/penicillamine.htm

    HiFD`JxPBLbdTljjZDp@ fda sheet

    HiFD`JxPBLbdTljjZDp@ FDA

    HiFD`JxPBLbdTljjZDp@ msds (material safety sheet)

    HiFD`JxPBLbdTljjZDp@ MSDS

    HiFD`JxPBLbdTljjZDp@ Synthesis Reference

    No information avaliable

    HiFD`JxPBLbdTljjZDp@ Molecular Weight

    149.212 g/mol

    HiFD`JxPBLbdTljjZDp@ Melting Point

    198.5 oC

    HiFD`JxPBLbdTljjZDp@ H2O Solubility

    1.11E+005 mg/L

    HiFD`JxPBLbdTljjZDp@ State

    Solid

    HiFD`JxPBLbdTljjZDp@ LogP

    -2.09

    HiFD`JxPBLbdTljjZDp@ Dosage Forms

    Capsule; Tablet

    HiFD`JxPBLbdTljjZDp@ Indication

    For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

    HiFD`JxPBLbdTljjZDp@ Pharmacology

    Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

    HiFD`JxPBLbdTljjZDp@ Absorption

    rapidly but incompletely

    HiFD`JxPBLbdTljjZDp@ Toxicity

    No information avaliable

    HiFD`JxPBLbdTljjZDp@ Patient Information

    No information avaliable

    HiFD`JxPBLbdTljjZDp@ Organisms Affected

    Humans and other mammals