Mercaptovaline
Category
Mercaptovaline Brand names, Mercaptovaline Analogs
Mercaptovaline Brand Names Mixture
No information avaliable
Mercaptovaline Chemical_Formula
C5H11NO2S
Mercaptovaline RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Mercaptovaline fda sheet
Mercaptovaline msds (material safety sheet)
Mercaptovaline Synthesis Reference
No information avaliable
Mercaptovaline Molecular Weight
149.212 g/mol
Mercaptovaline Melting Point
198.5 oC
Mercaptovaline H2O Solubility
1.11E+005 mg/L
Mercaptovaline State
Solid
Mercaptovaline LogP
-2.09
Mercaptovaline Dosage Forms
Capsule; Tablet
Mercaptovaline Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Mercaptovaline Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Mercaptovaline Absorption
rapidly but incompletely
Mercaptovaline Toxicity
No information avaliable
Mercaptovaline Patient Information
No information avaliable
Mercaptovaline Organisms Affected
Humans and other mammals
