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Distamine
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Distamine Brand names, Distamine Analogs

Distamine Brand Names Mixture

  • No information avaliable

Distamine Chemical_Formula

C5H11NO2S

Distamine RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

Distamine fda sheet

Distamine FDA

Distamine msds (material safety sheet)

Distamine MSDS

Distamine Synthesis Reference

No information avaliable

Distamine Molecular Weight

149.212 g/mol

Distamine Melting Point

198.5 oC

Distamine H2O Solubility

1.11E+005 mg/L

Distamine State

Solid

Distamine LogP

-2.09

Distamine Dosage Forms

Capsule; Tablet

Distamine Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

Distamine Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

Distamine Absorption

rapidly but incompletely

Distamine side effects and Toxicity

No information avaliable

Distamine Patient Information

No information avaliable

Distamine Organisms Affected

Humans and other mammals