Reduced_penicillamine
Category
Reduced_penicillamine Brand names, Reduced_penicillamine Analogs
Reduced_penicillamine Brand Names Mixture
No information avaliable
Reduced_penicillamine Chemical_Formula
C5H11NO2S
Reduced_penicillamine RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Reduced_penicillamine fda sheet
Reduced_penicillamine msds (material safety sheet)
Reduced_penicillamine Synthesis Reference
No information avaliable
Reduced_penicillamine Molecular Weight
149.212 g/mol
Reduced_penicillamine Melting Point
198.5 oC
Reduced_penicillamine H2O Solubility
1.11E+005 mg/L
Reduced_penicillamine State
Solid
Reduced_penicillamine LogP
-2.09
Reduced_penicillamine Dosage Forms
Capsule; Tablet
Reduced_penicillamine Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Reduced_penicillamine Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Reduced_penicillamine Absorption
rapidly but incompletely
Reduced_penicillamine Toxicity
No information avaliable
Reduced_penicillamine Patient Information
No information avaliable
Reduced_penicillamine Organisms Affected
Humans and other mammals
