Kuprenil
Category
Kuprenil Brand names, Kuprenil Analogs
Kuprenil Brand Names Mixture
No information avaliable
Kuprenil Chemical_Formula
C5H11NO2S
Kuprenil RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Kuprenil fda sheet
Kuprenil msds (material safety sheet)
Kuprenil Synthesis Reference
No information avaliable
Kuprenil Molecular Weight
149.212 g/mol
Kuprenil Melting Point
198.5 oC
Kuprenil H2O Solubility
1.11E+005 mg/L
Kuprenil State
Solid
Kuprenil LogP
-2.09
Kuprenil Dosage Forms
Capsule; Tablet
Kuprenil Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Kuprenil Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Kuprenil Absorption
rapidly but incompletely
Kuprenil Toxicity
No information avaliable
Kuprenil Patient Information
No information avaliable
Kuprenil Organisms Affected
Humans and other mammals
