Reduced_D-penicillamine
Category
Reduced_D-penicillamine Brand names, Reduced_D-penicillamine Analogs
Reduced_D-penicillamine Brand Names Mixture
No information avaliable
Reduced_D-penicillamine Chemical_Formula
C5H11NO2S
Reduced_D-penicillamine RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Reduced_D-penicillamine fda sheet
Reduced_D-penicillamine msds (material safety sheet)
Reduced_D-penicillamine Synthesis Reference
No information avaliable
Reduced_D-penicillamine Molecular Weight
149.212 g/mol
Reduced_D-penicillamine Melting Point
198.5 oC
Reduced_D-penicillamine H2O Solubility
1.11E+005 mg/L
Reduced_D-penicillamine State
Solid
Reduced_D-penicillamine LogP
-2.09
Reduced_D-penicillamine Dosage Forms
Capsule; Tablet
Reduced_D-penicillamine Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Reduced_D-penicillamine Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Reduced_D-penicillamine Absorption
rapidly but incompletely
Reduced_D-penicillamine Toxicity
No information avaliable
Reduced_D-penicillamine Patient Information
No information avaliable
Reduced_D-penicillamine Organisms Affected
Humans and other mammals
