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Depen Brand names, Depen Analogs

Depen Brand Names Mixture

  • No information avaliable

Depen Chemical_Formula

C5H11NO2S

Depen RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

Depen fda sheet

Depen FDA

Depen msds (material safety sheet)

Depen MSDS

Depen Synthesis Reference

No information avaliable

Depen Molecular Weight

149.212 g/mol

Depen Melting Point

198.5 oC

Depen H2O Solubility

1.11E+005 mg/L

Depen State

Solid

Depen LogP

-2.09

Depen Dosage Forms

Capsule; Tablet

Depen Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

Depen Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

Depen Absorption

rapidly but incompletely

Depen side effects and Toxicity

No information avaliable

Depen Patient Information

No information avaliable

Depen Organisms Affected

Humans and other mammals