Perdolat
Category
Perdolat Brand names, Perdolat Analogs
Perdolat Brand Names Mixture
No information avaliable
Perdolat Chemical_Formula
C5H11NO2S
Perdolat RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Perdolat fda sheet
Perdolat msds (material safety sheet)
Perdolat Synthesis Reference
No information avaliable
Perdolat Molecular Weight
149.212 g/mol
Perdolat Melting Point
198.5 oC
Perdolat H2O Solubility
1.11E+005 mg/L
Perdolat State
Solid
Perdolat LogP
-2.09
Perdolat Dosage Forms
Capsule; Tablet
Perdolat Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Perdolat Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Perdolat Absorption
rapidly but incompletely
Perdolat Toxicity
No information avaliable
Perdolat Patient Information
No information avaliable
Perdolat Organisms Affected
Humans and other mammals