mepivacaine hydrochloride
mepivacaine hydrochloride Brand names, mepivacaine hydrochloride Analogs
mepivacaine hydrochloride Brand Names Mixture
- No information avaliable
mepivacaine hydrochloride Chemical_Formula
C4H11N5
mepivacaine hydrochloride RX_link
http://www.rxlist.com/cgi/generic4/glumetza.htm
mepivacaine hydrochloride fda sheet
mepivacaine hydrochloride msds (material safety sheet)
mepivacaine hydrochloride Synthesis Reference
No information avaliable
mepivacaine hydrochloride Molecular Weight
129.164 g/mol
mepivacaine hydrochloride Melting Point
223-226 oC
mepivacaine hydrochloride H2O Solubility
Freely soluble as HCl salt
mepivacaine hydrochloride State
Solid
mepivacaine hydrochloride LogP
-0.267
mepivacaine hydrochloride Dosage Forms
Extended release tablet (500 mg or 1000 mg)
mepivacaine hydrochloride Indication
For use as an adjunct to diet and exercise to improve glycemic control in adult patients (18 years and older) with type 2 diabetes.
mepivacaine hydrochloride Pharmacology
Metformin is an antihyperglycemic agent, which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects and does not cause hyperinsulinemia. With metformin therapy, insulin secretion remains unchanged while fasting insulin levels and daylong plasma insulin response may actually decrease.
mepivacaine hydrochloride Absorption
Absorbed over 6 hours, bioavailability is 50 to 60% under fasting conditions. Food delays absorption.
mepivacaine hydrochloride side effects and Toxicity
Acute oral toxicity (LD50): 350 mg/kg [Rabbit]. It would be expected that adverse reactions of a more intense character including epigastric discomfort, nausea, and vomiting followed by diarrhea, drowsiness, weakness, dizziness, malaise and headache might be seen.
mepivacaine hydrochloride Patient Information
mepivacaine hydrochloride Organisms Affected
Humans and other mammals
