Scandicain
Scandicain Brand names, Scandicain Analogs
Scandicain Brand Names Mixture
- No information avaliable
Scandicain Chemical_Formula
C4H11N5
Scandicain RX_link
http://www.rxlist.com/cgi/generic4/glumetza.htm
Scandicain fda sheet
Scandicain msds (material safety sheet)
Scandicain Synthesis Reference
No information avaliable
Scandicain Molecular Weight
129.164 g/mol
Scandicain Melting Point
223-226 oC
Scandicain H2O Solubility
Freely soluble as HCl salt
Scandicain State
Solid
Scandicain LogP
-0.267
Scandicain Dosage Forms
Extended release tablet (500 mg or 1000 mg)
Scandicain Indication
For use as an adjunct to diet and exercise to improve glycemic control in adult patients (18 years and older) with type 2 diabetes.
Scandicain Pharmacology
Metformin is an antihyperglycemic agent, which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects and does not cause hyperinsulinemia. With metformin therapy, insulin secretion remains unchanged while fasting insulin levels and daylong plasma insulin response may actually decrease.
Scandicain Absorption
Absorbed over 6 hours, bioavailability is 50 to 60% under fasting conditions. Food delays absorption.
Scandicain side effects and Toxicity
Acute oral toxicity (LD50): 350 mg/kg [Rabbit]. It would be expected that adverse reactions of a more intense character including epigastric discomfort, nausea, and vomiting followed by diarrhea, drowsiness, weakness, dizziness, malaise and headache might be seen.
Scandicain Patient Information
Scandicain Organisms Affected
Humans and other mammals
