Scandonest Plain
Scandonest Plain Brand names, Scandonest Plain Analogs
Scandonest Plain Brand Names Mixture
- No information avaliable
Scandonest Plain Chemical_Formula
C4H11N5
Scandonest Plain RX_link
http://www.rxlist.com/cgi/generic4/glumetza.htm
Scandonest Plain fda sheet
Scandonest Plain msds (material safety sheet)
Scandonest Plain Synthesis Reference
No information avaliable
Scandonest Plain Molecular Weight
129.164 g/mol
Scandonest Plain Melting Point
223-226 oC
Scandonest Plain H2O Solubility
Freely soluble as HCl salt
Scandonest Plain State
Solid
Scandonest Plain LogP
-0.267
Scandonest Plain Dosage Forms
Extended release tablet (500 mg or 1000 mg)
Scandonest Plain Indication
For use as an adjunct to diet and exercise to improve glycemic control in adult patients (18 years and older) with type 2 diabetes.
Scandonest Plain Pharmacology
Metformin is an antihyperglycemic agent, which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects and does not cause hyperinsulinemia. With metformin therapy, insulin secretion remains unchanged while fasting insulin levels and daylong plasma insulin response may actually decrease.
Scandonest Plain Absorption
Absorbed over 6 hours, bioavailability is 50 to 60% under fasting conditions. Food delays absorption.
Scandonest Plain side effects and Toxicity
Acute oral toxicity (LD50): 350 mg/kg [Rabbit]. It would be expected that adverse reactions of a more intense character including epigastric discomfort, nausea, and vomiting followed by diarrhea, drowsiness, weakness, dizziness, malaise and headache might be seen.
Scandonest Plain Patient Information
Scandonest Plain Organisms Affected
Humans and other mammals
