Mepivacaine HCL
Mepivacaine HCL Brand names, Mepivacaine HCL Analogs
Mepivacaine HCL Brand Names Mixture
- No information avaliable
Mepivacaine HCL Chemical_Formula
C4H11N5
Mepivacaine HCL RX_link
http://www.rxlist.com/cgi/generic4/glumetza.htm
Mepivacaine HCL fda sheet
Mepivacaine HCL msds (material safety sheet)
Mepivacaine HCL Synthesis Reference
No information avaliable
Mepivacaine HCL Molecular Weight
129.164 g/mol
Mepivacaine HCL Melting Point
223-226 oC
Mepivacaine HCL H2O Solubility
Freely soluble as HCl salt
Mepivacaine HCL State
Solid
Mepivacaine HCL LogP
-0.267
Mepivacaine HCL Dosage Forms
Extended release tablet (500 mg or 1000 mg)
Mepivacaine HCL Indication
For use as an adjunct to diet and exercise to improve glycemic control in adult patients (18 years and older) with type 2 diabetes.
Mepivacaine HCL Pharmacology
Metformin is an antihyperglycemic agent, which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects and does not cause hyperinsulinemia. With metformin therapy, insulin secretion remains unchanged while fasting insulin levels and daylong plasma insulin response may actually decrease.
Mepivacaine HCL Absorption
Absorbed over 6 hours, bioavailability is 50 to 60% under fasting conditions. Food delays absorption.
Mepivacaine HCL side effects and Toxicity
Acute oral toxicity (LD50): 350 mg/kg [Rabbit]. It would be expected that adverse reactions of a more intense character including epigastric discomfort, nausea, and vomiting followed by diarrhea, drowsiness, weakness, dizziness, malaise and headache might be seen.
Mepivacaine HCL Patient Information
Mepivacaine HCL Organisms Affected
Humans and other mammals
