S-Ropivacaine Mesylate
Brand names,
S-Ropivacaine Mesylate
Analogs
S-Ropivacaine Mesylate
Brand Names Mixture
S-Ropivacaine Mesylate
Chemical_Formula
C4H11N5
S-Ropivacaine Mesylate
RX_link
http://www.rxlist.com/cgi/generic4/glumetza.htm
S-Ropivacaine Mesylate
fda sheet
S-Ropivacaine Mesylate
msds (material safety sheet)
S-Ropivacaine Mesylate
Synthesis Reference
No information avaliable
S-Ropivacaine Mesylate
Molecular Weight
129.164 g/mol
S-Ropivacaine Mesylate
Melting Point
223-226 oC
S-Ropivacaine Mesylate
H2O Solubility
Freely soluble as HCl salt
S-Ropivacaine Mesylate
State
Solid
S-Ropivacaine Mesylate
LogP
-0.267
S-Ropivacaine Mesylate
Dosage Forms
Extended release tablet (500 mg or 1000 mg)
S-Ropivacaine Mesylate
Indication
For use as an adjunct to diet and exercise to improve glycemic control in adult patients (18 years and older) with type 2 diabetes.
S-Ropivacaine Mesylate
Pharmacology
Metformin is an antihyperglycemic agent, which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects and does not cause hyperinsulinemia. With metformin therapy, insulin secretion remains unchanged while fasting insulin levels and daylong plasma insulin response may actually decrease.
S-Ropivacaine Mesylate
Absorption
Absorbed over 6 hours, bioavailability is 50 to 60% under fasting conditions. Food delays absorption.
S-Ropivacaine Mesylate
side effects and Toxicity
Acute oral toxicity (LD50): 350 mg/kg [Rabbit]. It would be expected that adverse reactions of a more intense character including epigastric discomfort, nausea, and vomiting followed by diarrhea, drowsiness, weakness, dizziness, malaise and headache might be seen.
S-Ropivacaine Mesylate
Patient Information
S-Ropivacaine Mesylate
Organisms Affected
Humans and other mammals