Scandicaine
Scandicaine Brand names, Scandicaine Analogs
Scandicaine Brand Names Mixture
- No information avaliable
Scandicaine Chemical_Formula
C4H11N5
Scandicaine RX_link
http://www.rxlist.com/cgi/generic4/glumetza.htm
Scandicaine fda sheet
Scandicaine msds (material safety sheet)
Scandicaine Synthesis Reference
No information avaliable
Scandicaine Molecular Weight
129.164 g/mol
Scandicaine Melting Point
223-226 oC
Scandicaine H2O Solubility
Freely soluble as HCl salt
Scandicaine State
Solid
Scandicaine LogP
-0.267
Scandicaine Dosage Forms
Extended release tablet (500 mg or 1000 mg)
Scandicaine Indication
For use as an adjunct to diet and exercise to improve glycemic control in adult patients (18 years and older) with type 2 diabetes.
Scandicaine Pharmacology
Metformin is an antihyperglycemic agent, which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects and does not cause hyperinsulinemia. With metformin therapy, insulin secretion remains unchanged while fasting insulin levels and daylong plasma insulin response may actually decrease.
Scandicaine Absorption
Absorbed over 6 hours, bioavailability is 50 to 60% under fasting conditions. Food delays absorption.
Scandicaine side effects and Toxicity
Acute oral toxicity (LD50): 350 mg/kg [Rabbit]. It would be expected that adverse reactions of a more intense character including epigastric discomfort, nausea, and vomiting followed by diarrhea, drowsiness, weakness, dizziness, malaise and headache might be seen.
Scandicaine Patient Information
Scandicaine Organisms Affected
Humans and other mammals
